Publications

Our group publishes papers presenting new methodologies, describing the results of studies that use our software, and reviewing current topics in the field of Bioinformatics. Scroll down or click here for a complete list of papers produced by our lab. Since 2013, we write blog posts summarizing new research papers and review articles:

GWAS

Mouse Genetics

Population Structure

Review Articles

Publications

226 entries « 1 of 5 »

2019

LaPierre, Nathan; Mangul, Serghei; Alser, Mohammed; Mandric, Igor; Wu, Nicholas C; Koslicki, David; Eskin, Eleazar

MiCoP: microbial community profiling method for detecting viral and fungal organisms in metagenomic samples. Journal Article

BMC Genomics, 20 (Suppl 5), pp. 423, 2019, ISSN: 1471-2164.

Abstract | Links | BibTeX | Tags:

Mangul, Serghei; Martin, Lana S; Eskin, Eleazar; Blekhman, Ran

Improving the usability and archival stability of bioinformatics software. Journal Article

Genome Biol, 20 (1), pp. 47, 2019, ISSN: 1474-760X.

Abstract | Links | BibTeX | Tags:

Duong, Dat; Ahmad, Wasi Uddin; Eskin, Eleazar; Chang, Kai-Wei W; Li, Jingyi Jessica

Word and Sentence Embedding Tools to Measure Semantic Similarity of Gene Ontology Terms by Their Definitions. Journal Article

J Comput Biol, 26 (1), pp. 38-52, 2019, ISSN: 1557-8666.

Abstract | Links | BibTeX | Tags:

Mangul, Serghei; Martin, Lana S; Langmead, Ben; Sanchez-Galan, Javier E; Toma, Ian; Hormozdiari, Fereydoun; Pevzner, Pavel; Eskin, Eleazar

How bioinformatics and open data can boost basic science in countries and universities with limited resources. Journal Article

Nat Biotechnol, 37 (3), pp. 324-326, 2019, ISSN: 1546-1696.

Links | BibTeX | Tags:

Mangul, Serghei; Martin, Lana S; Hill, Brian L; Lam, Angela Ka-Mei; Distler, Margaret G; Zelikovsky, Alex; Eskin, Eleazar; Flint, Jonathan

Systematic benchmarking of omics computational tools. Journal Article

Nat Commun, 10 (1), pp. 1393, 2019, ISSN: 2041-1723.

Abstract | Links | BibTeX | Tags:

Mangul, Serghei; Mosqueiro, Thiago; Abdill, Richard J; Duong, Dat; Mitchell, Keith; Sarwal, Varuni; Hill, Brian; Brito, Jaqueline; Littman, Russell Jared; Statz, Benjamin; Lam, Angela Ka-Mei; Dayama, Gargi; Grieneisen, Laura; Martin, Lana S; Flint, Jonathan; Eskin, Eleazar; Blekhman, Ran

Challenges and recommendations to improve the installability and archival stability of omics computational tools. Journal Article

PLoS Biol, 17 (6), pp. e3000333, 2019, ISSN: 1545-7885.

Abstract | Links | BibTeX | Tags:

2018

Gai, Lisa; Eskin, Eleazar

Finding associated variants in genome-wide association studies on multiple traits. Journal Article

Bioinformatics, 34 (13), pp. i467-i474, 2018, ISSN: 1367-4811.

Abstract | Links | BibTeX | Tags: Multiple Phenotypes

Hormozdiari, Farhad I; Jung, Junghyun; Eskin, Eleazar; Joo, Jong Wha J

Leveraging allelic heterogeneity to increase power of association testing Journal Article

bioRxiv, pp. 498360, 2018.

Abstract | Links | BibTeX | Tags: Alleliec Heterogeneity, Association Study Methods, Multi-SNP Association

Kennedy, Elizabeth M; Goehring, George N; Nichols, Michael H; Robins, Chloe; Mehta, Divya; Klengel, Torsten; Eskin, Eleazar; Smith, Alicia K; Conneely, Karen N

An integrated -omics analysis of the epigenetic landscape of gene expression in human blood cells. Journal Article

BMC Genomics, 19 (1), pp. 476, 2018, ISSN: 1471-2164.

Abstract | Links | BibTeX | Tags:

Kang, Eun Yong; Lee, Cue Hyunkyu; Furlotte, Nicholas A; Joo, Jong Wha J; Kostem, Emrah; Zaitlen, Noah; Eskin, Eleazar; Han, Buhm

An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures. Journal Article

Genetics, 2018, ISSN: 1943-2631.

Abstract | Links | BibTeX | Tags: Association Study Methods, Meta-Analysis

Mangul, Serghei; Yang, Harry Taegyun; Strauli, Nicolas; Gruhl, Franziska; Porath, Hagit T; Hsieh, Kevin; Chen, Linus; Daley, Timothy; Christenson, Stephanie; Wesolowska-Andersen, Agata; Spreafico, Roberto; Rios, Cydney; Eng, Celeste; Smith, Andrew D; Hernandez, Ryan D; Ophoff, Roel A; Santana, Jose Rodriguez; Levanon, Erez Y; Woodruff, Prescott G; Burchard, Esteban; Seibold, Max A; Shifman, Sagiv; Eskin, Eleazar; Zaitlen, Noah

ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues. Journal Article

Genome Biol, 19 (1), pp. 36, 2018, ISSN: 1474-760X.

Abstract | Links | BibTeX | Tags: RNAseq

Rahmani, Elior; Schweiger, Regev; Shenhav, Liat; Wingert, Theodora; Hofer, Ira; Gabel, Eilon; Eskin, Eleazar; Halperin, Eran

BayesCCE: a Bayesian framework for estimating cell-type composition from DNA methylation without the need for methylation reference. Journal Article

Genome Biol, 19 (1), pp. 141, 2018, ISSN: 1474-760X.

Abstract | Links | BibTeX | Tags:

Wu, Yue; Hormozdiari, Farhad; Joo, Jong Wha J; Eskin, Eleazar

Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies. Journal Article

J Comput Biol, 2018, ISSN: 1557-8666.

Abstract | Links | BibTeX | Tags: Imputation

Mangul, Serghei; Martin, Lana S; Eskin, Eleazar

Involving undergraduates in genomics research to narrow the education-research gap. Journal Article

Nat Biotechnol, 36 (4), pp. 369-371, 2018, ISSN: 1546-1696.

Links | BibTeX | Tags:

Gamazon, Eric R; Segrè, Ayellet V; van de Bunt, Martijn; Wen, Xiaoquan; Xi, Hualin S; Hormozdiari, Farhad; Ongen, Halit; Konkashbaev, Anuar; Derks, Eske M; Aguet, François; Quan, Jie; Nicolae, Dan L; Eskin, Eleazar; Kellis, Manolis; Getz, Gad; McCarthy, Mark I; Dermitzakis, Emmanouil T; Cox, Nancy J; Ardlie, Kristin G

Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation. Journal Article

Nat Genet, 50 (7), pp. 956-967, 2018, ISSN: 1546-1718.

Abstract | Links | BibTeX | Tags: Co-Localization, Expression QTLs, Fine Mapping, GWAS+eQTL

Hormozdiari, Farhad; Gazal, Steven; van de Geijn, Bryce; Finucane, Hilary K; Ju, Chelsea J-T; Loh, Po-Ru R; Schoech, Armin; Reshef, Yakir; Liu, Xuanyao; O'Connor, Luke; Gusev, Alexander; Eskin, Eleazar; Price, Alkes L

Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits. Journal Article

Nat Genet, 50 (7), pp. 1041-1047, 2018, ISSN: 1546-1718.

Abstract | Links | BibTeX | Tags: Fine Mapping, Functional Genomics

Sul, Jae Hoon; Martin, Lana S; Eskin, Eleazar

Population structure in genetic studies: Confounding factors and mixed models. Journal Article

PLoS Genet, 14 (12), pp. e1007309, 2018, ISSN: 1553-7404.

Abstract | Links | BibTeX | Tags: Mixed Models, Population Structure Methods

Loohuis, Loes Olde M; Mangul, Serghei; Ori, Anil P S; Jospin, Guillaume; Koslicki, David; Yang, Harry Taegyun; Wu, Timothy; Boks, Marco P; Lomen-Hoerth, Catherine; Wiedau-Pazos, Martina; Cantor, Rita M; de Vos, Willem M; Kahn, René S; Eskin, Eleazar; Ophoff, Roel A

Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia. Journal Article

Transl Psychiatry, 8 (1), pp. 96, 2018, ISSN: 2158-3188.

Abstract | Links | BibTeX | Tags:

2017

Robert Brown Gleb Kichaev, Nicholas Mancuso James Boocock ; Pasaniuc, Bogdan

Enhanced methods to detect haplotypic effects on gene expression Journal Article

Bioinformatics, pp. btx142, 2017.

Links | BibTeX | Tags:

Ritchie, Marylyn D; Davis, Joe R; Aschard, Hugues; Battle, Alexis; Conti, David; Du, Mengmeng; Eskin, Eleazar; Fallin, Daniele M; Hsu, Li; Kraft, Peter; Moore, Jason H; Pierce, Brandon L; Bien, Stephanie A; Thomas, Duncan C; Wei, Peng; Montgomery, Stephen B

Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions. Journal Article

Am J Epidemiol, 186 (7), pp. 771-777, 2017, ISSN: 1476-6256.

Abstract | Links | BibTeX | Tags: Genes By Environment

Hormozdiari, Farhad; Zhu, Anthony; Kichaev, Gleb; Ju, Chelsea J-T; Segrè, Ayellet V; Joo, Jong Wha J; Won, Hyejung; Sankararaman, Sriram; Pasaniuc, Bogdan; Shifman, Sagiv; Eskin, Eleazar

Widespread Allelic Heterogeneity in Complex Traits. Journal Article

Am J Hum Genet, 100 (5), pp. 789-802, 2017, ISSN: 1537-6605.

Abstract | Links | BibTeX | Tags: Fine Mapping

Duong, Dat; Gai, Lisa; Snir, Sagi; Kang, Eun Yong; Han, Buhm; Sul, Jae Hoon; Eskin, Eleazar

Applying meta-analysis to genotype-tissue expression data from multiple tissues to identify eQTLs and increase the number of eGenes. Journal Article

Bioinformatics, 33 (14), pp. i67-i74, 2017, ISSN: 1367-4811.

Abstract | Links | BibTeX | Tags: Expression QTLs, Meta-Analysis

Lee, C H; Eskin, E; Han, B

Increasing the power of meta-analysis of genome-wide association studies to detect heterogeneous effects. Journal Article

Bioinformatics, 33 (14), pp. i379-i388, 2017, ISSN: 1367-4811.

Abstract | Links | BibTeX | Tags: Meta-Analysis

Lozano, Jose A; Hormozdiari, Farhad; Joo, Jong Wha; Han, Buhm; Eskin, Eleazar

The Multivariate Normal Distribution Framework for Analyzing Association Studies Journal Article

bioRxiv, pp. 208199, 2017.

Abstract | Links | BibTeX | Tags: Fine Mapping, Multi-SNP Association, Multiple Testing

Park, Danny S; Eskin, Itamar; Kang, Eun Yong; Gamazon, Eric R; Eng, Celeste; Gignoux, Christopher R; Galanter, Joshua M; Burchard, Esteban; Ye, Chun J; Aschard, Hugues; Eskin, Eleazar; Halperin, Eran; Zaitlen, Noah

An ancestry-based approach for detecting interactions. Journal Article

Genet Epidemiol, 2017, ISSN: 1098-2272.

Abstract | Links | BibTeX | Tags: Ancestry Mapping, Gene-Gene Interactions

Bilow, Michael; Crespo, Fernando; Pan, Zhicheng; Eskin, Eleazar; Eyheramendy, Susana

Simultaneous Modeling of Disease Status and Clinical Phenotypes To Increase Power in Genome-Wide Association Studies. Journal Article

Genetics, 205 (3), pp. 1041-1047, 2017, ISSN: 1943-2631.

Abstract | Links | BibTeX | Tags: Causal Inference Biology, Covariates

Mangul, Serghei; Yang, Harry Taegyun; Hormozdiari, Farhad; Dainis, Alex; Tseng, Elizabeth; Ashley, Euan A; Zelikovsky, Alex; Eskin, Eleazar

HapIso : An Accurate Method for the Haplotype-Specific Isoforms Reconstruction from Long Single-Molecule Reads. Journal Article

IEEE Trans Nanobioscience, 16 (2), pp. 108-115, 2017, ISSN: 1558-2639.

Abstract | Links | BibTeX | Tags: Allele Specific Expression, Haplotype Phasing, Haplotyping from Sequences, RNAseq, Sequence Assembly

He, Dan; Wang, Zhanyong; Parida, Laxmi; Eskin, Eleazar

IPED2: Inheritance Path based Pedigree Reconstruction Algorithm for Complicated Pedigrees. Journal Article

IEEE/ACM Trans Comput Biol Bioinform, 2017, ISSN: 1557-9964.

Abstract | Links | BibTeX | Tags: Pedigree Inference

Buckley, Matthew T; Racimo, Fernando; Allentoft, Morten E; Jensen, Majken K; Jonsson, Anna; Huang, Hongyan; Hormozdiari, Farhad; Sikora, Martin; Marnetto, Davide; Eskin, Eleazar; Jørgensen, Marit E; Grarup, Niels; Pedersen, Oluf; Hansen, Torben; Kraft, Peter; Willerslev, Eske; Nielsen, Rasmus

Selection in Europeans on fatty acid desaturases associated with dietary changes. Journal Article

Mol Biol Evol, 2017, ISSN: 1537-1719.

Abstract | Links | BibTeX | Tags:

Jasinska, Anna J; Zelaya, Ivette; Service, Susan K; Peterson, Christine B; Cantor, Rita M; Choi, Oi-Wa W; DeYoung, Joseph; Eskin, Eleazar; Fairbanks, Lynn A; Fears, Scott; Furterer, Allison E; Huang, Yu S; Ramensky, Vasily; Schmitt, Christopher A; Svardal, Hannes; Jorgensen, Matthew J; Kaplan, Jay R; Villar, Diego; Aken, Bronwen L; Flicek, Paul; Nag, Rishi; Wong, Emily S; Blangero, John; Dyer, Thomas D; Bogomolov, Marina; Benjamini, Yoav; Weinstock, George M; Dewar, Ken; Sabatti, Chiara; Wilson, Richard K; Jentsch, David J; Warren, Wesley; Coppola, Giovanni; Woods, Roger P; Freimer, Nelson B

Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate. Journal Article

Nat Genet, 49 (12), pp. 1714-1721, 2017, ISSN: 1546-1718.

Abstract | Links | BibTeX | Tags:

Rahmani, Elior; Zaitlen, Noah; Baran, Yael; Eng, Celeste; Hu, Donglei; Galanter, Joshua; Oh, Sam; Burchard, Esteban G; Eskin, Eleazar; Zou, James; Halperin, Eran

Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation. Journal Article

Nat Methods, 14 (3), pp. 218-219, 2017, ISSN: 1548-7105.

Links | BibTeX | Tags: Confounding

Crawford, Nicholas G; Kelly, Derek E; Hansen, Matthew E B; Beltrame, Marcia H; Fan, Shaohua; Bowman, Shanna L; Jewett, Ethan; Ranciaro, Alessia; Thompson, Simon; Lo, Yancy; Pfeifer, Susanne P; Jensen, Jeffrey D; Campbell, Michael C; Beggs, William; Hormozdiari, Farhad; Mpoloka, Sununguko Wata; Mokone, Gaonyadiwe George; Nyambo, Thomas; Meskel, Dawit Wolde; Belay, Gurja; Haut, Jake; Rothschild, Harriet; Zon, Leonard; Zhou, Yi; Kovacs, Michael A; Xu, Mai; Zhang, Tongwu; Bishop, Kevin; Sinclair, Jason; Rivas, Cecilia; Elliot, Eugene; Choi, Jiyeon; Li, Shengchao A; Hicks, Belynda; Burgess, Shawn; Abnet, Christian; Watkins-Chow, Dawn E; Oceana, Elena; Song, Yun S; Eskin, Eleazar; Brown, Kevin M; Marks, Michael S; Loftus, Stacie K; Pavan, William J; Yeager, Meredith; Chanock, Stephen; Tishkoff, Sarah A

Loci associated with skin pigmentation identified in African populations. Journal Article

Science, 358 (6365), 2017, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags:

Mangul, Serghei; Martin, Lana S; Hoffmann, Alexander; Pellegrini, Matteo; Eskin, Eleazar

Addressing the Digital Divide in Contemporary Biology: Lessons from Teaching UNIX. Journal Article

Trends Biotechnol, 2017, ISSN: 1879-3096.

Abstract | Links | BibTeX | Tags:

2016

Mangul, Serghei; Loohuis, Loes Olde M; Ori, Anil; Jospin, Guillaume; Koslicki, David; Yang, Harry Taegyun; Wu, Timothy; Boks, Marco P; Lomen-Hoerth, Catherine; Wiedau-Pazos, Martina; Cantor, Rita; de Vos, Willem M; Kahn, Rene S; Eskin, Eleazar; Ophoff, Roel A

Total RNA Sequencing reveals microbial communities in human blood and disease specific effects. Journal Article

BioRxiv, (057570), 2016.

Abstract | Links | BibTeX | Tags: blood microbiome, RNA sequencing, schizophrenia, unmapped reads

Mangul, Serghei; Yang, Harry Taegyun; Strauli, Nicolas; Gruhl, Franziska; Daley, Timothy; Christenson, Stephanie; Andersen, Agata Wesolowska; Spreafico, Roberto; Rios, Cydney; Eng, Celeste; Smith, Andrew D; Hernandez, Ryan D; Ophoff, Roel A; Santana, Jose Rodriguez; Woodruff, Prescott G; Burchard, Esteban; Seibold, Max A; Shifman, Sagiv; Eskin, Eleazar; Zaitlen, Noah

Dumpster diving in RNA-sequencing to find the source of every last read. Journal Article

BioRxiv, 2016.

Links | BibTeX | Tags: read origin protocol, RNA sequencing, unmapped reads

Han, Buhm; Duong, Dat; Sul, Jae Hoon; de Bakker, Paul I W; Eskin, Eleazar; Raychaudhuri, Soumya

A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping. Journal Article

Hum Mol Genet, 2016, ISSN: 1460-2083.

Abstract | Links | BibTeX | Tags: eQTL, genome-wide association studies, Meta-Analysis

Sul, Jae Hoon; Bilow, Michael; Yang, Wen-Yun Y; Kostem, Emrah; Furlotte, Nick; He, Dan; Eskin, Eleazar

Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models. Journal Article

PLoS Genet, 12 (3), pp. e1005849, 2016, ISSN: 1553-7404.

Abstract | Links | BibTeX | Tags: gene-by-environment interactions, genome-wide association studies, Mixed Models

Joo, Jong Wha J; Hormozdiari, Farhad; Han, Buhm; Eskin, Eleazar

Multiple testing correction in linear mixed models. Journal Article

Genome Biol, 17 (1), pp. 62, 2016, ISSN: 1474-760X.

Abstract | Links | BibTeX | Tags: genome-wide association studies, Mixed Models, Multiple Testing

Lusis, Aldons J; Seldin, Marcus; Allayee, Hooman; Bennett, Brian J; Civelek, Mete; Davis, Richard C; Eskin, Eleazar; Farber, Charles; Hui, Simon T; Mehrabian, Margarete; Norheim, Frode; Pan, Calvin; Parks, Brian; Rau, Christoph; Smith, Desmond J; Vallim, Thomas; Wang, Yibin; Wang, Jessica

The Hybrid Mouse Diversity Panel: A Resource for Systems Genetics Analyses of Metabolic and Cardiovascular Traits. Journal Article

J Lipid Res, 2016, ISSN: 1539-7262.

Abstract | Links | BibTeX | Tags: genome-wide association studies, Hybrid Mouse Diversity Panel, Mouse Genetics

Mangul, Serghei ; Yang, Harry ; Hormozdiari, Farhad ; Tseng, Elizabeth ; Zelikovsky, Alex ; Eskin, Eleazar

HapIso: An Accurate Method for the Haplotype-Specific Isoforms Reconstruction from Long Single-Molecule Reads Book Chapter

Bioinformatics Research and Applications, pp. 80-92, Springer International Publishing, 2016.

Links | BibTeX | Tags: RNAseq;Haplotyping from Sequences

Hormozdiari, Farhad ; Kang, Eun Yong ; Bilow, Michael ; Ben-David, Eyal ; Vulpe, Chris ; McLachlan, Stela ; Lusis, Aldons J; Han, Buhm ; Eskin, Eleazar

Imputing Phenotypes for Genome-wide Association Studies. Journal Article

Am J Hum Genet, 99 (1), pp. 89-103, 2016, ISSN: 1537-6605.

Abstract | Links | BibTeX | Tags: Multiple Phenotypes;Imputation

Duong, Dat ; Zou, Jennifer ; Hormozdiari, Farhad ; Sul, Jae Hoon ; Ernst, Jason ; Han, Buhm ; Eskin, Eleazar

Using genomic annotations increases statistical power to detect eGenes. Journal Article

Bioinformatics, 32 (12), pp. i156-i163, 2016, ISSN: 1367-4811.

Abstract | Links | BibTeX | Tags: Expression QTLs

Kang, Eun Yong; Park, Yurang; Li, Xiao; Segrè, Ayellet V; Han, Buhm; Eskin, Eleazar

ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity between Studies in Meta-analysis. Journal Article

G3 (Bethesda), 6 (7), pp. 1793-8, 2016, ISSN: 2160-1836.

Abstract | Links | BibTeX | Tags: Expression QTLs;Meta-Analysis

Won, Hyejung; de la Torre-Ubieta, Luis; Stein, Jason L; Parikshak, Neelroop N; Huang, Jerry; Opland, Carli K; Gandal, Michael J; Sutton, Gavin J; Hormozdiari, Farhad; Lu, Daning; Lee, Changhoon; Eskin, Eleazar; Voineagu, Irina; Ernst, Jason; Geschwind, Daniel H

Chromosome conformation elucidates regulatory relationships in developing human brain. Journal Article

Nature, 538 (7626), pp. 523-527, 2016, ISSN: 1476-4687.

Abstract | Links | BibTeX | Tags: Fine Mapping

Kang, Eun Yong; Martin, Lisa; Mangul, Serghei; Isvilanonda, Warin; Zou, Jennifer; Ben-David, Eyal; Han, Buhm; Lusis, Aldons J; Shifman, Sagiv; Eskin, Eleazar

Discovering SNPs Regulating Human Gene Expression Using Allele Specific Expression from RNA-Seq Data. Journal Article

Genetics, 2016, ISSN: 1943-2631.

Abstract | Links | BibTeX | Tags: Allele Specific Expression, Expression QTLs

Artyomenko, Alexander; Wu, Nicholas C; Mangul, Serghei; Eskin, Eleazar; Sun, Ren; Zelikovsky, Alex

Long Single-Molecule Reads Can Resolve the Complexity of the Influenza Virus Composed of Rare, Closely Related Mutant Variants Book Chapter

Research in Computational Molecular Biology, pp. 164-175, Springer International Publishing, 2016.

Links | BibTeX | Tags: Virus Genomics;Virus Assembly

Hormozdiari, Farhad; van de Bunt, Martijn; Segrè, Ayellet V; Li, Xiao; Joo, Jong Wha J; Bilow, Michael; Sul, Jae Hoon; Sankararaman, Sriram; Pasaniuc, Bogdan; Eskin, Eleazar

Colocalization of GWAS and eQTL Signals Detects Target Genes. Journal Article

Am J Hum Genet, 2016, ISSN: 1537-6605.

Abstract | Links | BibTeX | Tags: Expression QTLs, Fine Mapping

Joo, Jong Wha J; Kang, Eun Yong; Org, Elin; Furlotte, Nick; Parks, Brian; Hormozdiari, Farhad; Lusis, Aldons J; Eskin, Eleazar

Efficient and Accurate Multiple-Phenotype Regression Method for High Dimensional Data Considering Population Structure. Journal Article

Genetics, 204 (4), pp. 1379-1390, 2016, ISSN: 1943-2631.

Abstract | Links | BibTeX | Tags: Mixed Models, Multiple Phenotypes

Won, Hyejung ; de la Torre-Ubieta, Luis ; Stein, Jason L; Parikshak, Neelroop N; Huang, Jerry ; Opland, Carli K; Gandal, Michael J; Sutton, Gavin J; Hormozdiari, Farhad ; Lu, Daning ; Lee, Changhoon ; Eskin, Eleazar ; Voineagu, Irina ; Ernst, Jason ; Geschwind, Daniel H

Chromosome conformation elucidates regulatory relationships in developing human brain. Journal Article

Nature, 538 (7626), pp. 523-527, 2016, ISSN: 1476-4687.

Abstract | Links | BibTeX | Tags: Fine Mapping

Artyomenko, Alexander ; Wu, Nicholas C; Mangul, Serghei ; Eskin, Eleazar ; Sun, Ren ; Zelikovsky, Alex

Long Single-Molecule Reads Can Resolve the Complexity of the Influenza Virus Composed of Rare, Closely Related Mutant Variants Book Chapter

Research in Computational Molecular Biology, pp. 164-175, Springer International Publishing, 2016.

Links | BibTeX | Tags: Virus Genomics;Virus Assembly

226 entries « 1 of 5 »