Publications

Our group publishes papers presenting new methodologies, describing the results of studies that use our software, and reviewing current topics in the field of Bioinformatics. Scroll down or click here for a complete list of papers produced by our lab. Since 2013, we write blog posts summarizing new research papers and review articles:

GWAS

Mouse Genetics

Population Structure

Review Articles

Publications

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2016

Han, Buhm; Duong, Dat; Sul, Jae Hoon; de Bakker, Paul I W; Eskin, Eleazar; Raychaudhuri, Soumya

A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping. Journal Article

Hum Mol Genet, 2016, ISSN: 1460-2083.

Abstract | Links | BibTeX | Tags: eQTL, genome-wide association studies, Meta-Analysis

Sul, Jae Hoon; Bilow, Michael; Yang, Wen-Yun Y; Kostem, Emrah; Furlotte, Nick; He, Dan; Eskin, Eleazar

Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models. Journal Article

PLoS Genet, 12 (3), pp. e1005849, 2016, ISSN: 1553-7404.

Abstract | Links | BibTeX | Tags: gene-by-environment interactions, genome-wide association studies, Mixed Models

Joo, Jong Wha J; Hormozdiari, Farhad; Han, Buhm; Eskin, Eleazar

Multiple testing correction in linear mixed models. Journal Article

Genome Biol, 17 (1), pp. 62, 2016, ISSN: 1474-760X.

Abstract | Links | BibTeX | Tags: genome-wide association studies, Mixed Models, Multiple Testing

Lusis, Aldons J; Seldin, Marcus; Allayee, Hooman; Bennett, Brian J; Civelek, Mete; Davis, Richard C; Eskin, Eleazar; Farber, Charles; Hui, Simon T; Mehrabian, Margarete; Norheim, Frode; Pan, Calvin; Parks, Brian; Rau, Christoph; Smith, Desmond J; Vallim, Thomas; Wang, Yibin; Wang, Jessica

The Hybrid Mouse Diversity Panel: A Resource for Systems Genetics Analyses of Metabolic and Cardiovascular Traits. Journal Article

J Lipid Res, 2016, ISSN: 1539-7262.

Abstract | Links | BibTeX | Tags: genome-wide association studies, Hybrid Mouse Diversity Panel, Mouse Genetics

2015

Lavinsky, Joel; Crow, Amanda L; Pan, Calvin; Wang, Juemei; Aaron, Ksenia A; Ho, Maria K; Li, Qingzhong; Salehide, Pehzman; Myint, Anthony; Monges-Hernadez, Maya; Eskin, Eleazar; Allayee, Hooman; Lusis, Aldons J; Friedman, Rick A

Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss. Journal Article

11 (6), pp. e1005293, 2015, ISSN: 1553-7404.

Links | BibTeX | Tags: cochlear function, genome-wide association studies

Joo, Jong Wha J; Kang, Eun Yong; Org, Elin; Furlotte, Nick; Parks, Brian; Lusis, Aldons J; Eskin, Eleazar

Efficient and Accurate Multiple-Phenotypes Regression Method for High Dimensional Data Considering Population Structure Book Chapter

Research in Computational Molecular Biology, pp. 136-153, Springer International Publishing, 2015.

Abstract | Links | BibTeX | Tags: GAMMA, genome-wide association studies, microbiome

Wang, Zhanyong; Sul, Jae Hoon; Snir, Sagi; Lozano, Jose A; Eskin, Eleazar

Gene-Gene Interactions Detection Using a Two-stage Model. Journal Article

J Comput Biol, 22 (6), pp. 563-76, 2015, ISSN: 1557-8666.

Abstract | Links | BibTeX | Tags: genome-wide association studies, Threshold-based Efficient Pairwise Association Approach

Luykx, J J; Bakker, S C; Visser, W F; Verhoeven-Duif, N; Buizer-Voskamp, J E; den Heijer, J M; Boks, M P M; Sul, J H; Eskin, E; Ori, A P; Cantor, R M; Vorstman, J; Strengman, E; DeYoung, J; Kappen, T H; Pariama, E; van Dongen, E P A; Borgdorff, P; Bruins, P; de Koning, T J; Kahn, R S; Ophoff, R A

Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma. Journal Article

Mol Psychiatry, 2015, ISSN: 1476-5578.

Abstract | Links | BibTeX | Tags: genome-wide association studies, NMDAR, schizophrenia

Crow, Amanda L; Ohmen, Jeffrey; Wang, Juemei; Lavinsky, Joel; Hartiala, Jaana; Li, Qingzhong; Li, Xin; Salehide, Pezhman; Eskin, Eleazar; Pan, Calvin; Lusis, Aldons J; Allayee, Hooman; Friedman, Rick A

The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency Specific Genetic Determinants. Journal Article

G3 (Bethesda), 2015, ISSN: 2160-1836.

Abstract | Links | BibTeX | Tags: cochlear function, genome-wide association studies, phenotypic heterogeneity

Bennett, Brian J; Davis, Richard C; Civelek, Mete; Orozco, Luz; Wu, Judy; Qi, Hannah; Pan, Calvin; Packard, René Sevag R; Eskin, Eleazar; Yan, Mujing; Kirchgessner, Todd; Wang, Zeneng; Li, Xinmin; Gregory, Jill C; Hazen, Stanley L; Gargalovic, Peter S; JLusis, Aldons

Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. Journal Article

PLoS Genet, 11 (12), pp. e1005711, 2015, ISSN: 1553-7404.

Abstract | Links | BibTeX | Tags: atherosclerosis, genome-wide association studies, HMDP