Publications

Our group publishes papers presenting new methodologies, describing the results of studies that use our software, and reviewing current topics in the field of Bioinformatics. Scroll down or click here for a complete list of papers produced by our lab. Since 2013, we write blog posts summarizing new research papers and review articles:

GWAS

Mouse Genetics

Population Structure

Review Articles

Publications

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2015

Rau, Christoph D; Parks, Brian; Wang, Yibin; Eskin, Eleazar; Simecek, Petr; Churchill, Gary A; Lusis, Aldons J

High Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. Journal Article

G3 (Bethesda), 5 (10), pp. 2021-6, 2015, ISSN: 2160-1836.

Abstract | Links | BibTeX | Tags: HMDP, Mouse Genetics

Zhou, Xiaoying; Crow, Amanda L; Hartiala, Jaana; Spindler, Tassja J; Ghazalpour, Anatole; Barsky, Lora W; Bennett, Brian J; Parks, Brian W; Eskin, Eleazar; Jain, Rajan; Epstein, Jonathan A; Lusis, Aldons J; Adams, Gregor B; Allayee, Hooman

The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice. Journal Article

Stem Cell Reports, 5 (1), pp. 125-38, 2015, ISSN: 2213-6711.

Abstract | Links | BibTeX | Tags: HMDP

Bennett, Brian J; Davis, Richard C; Civelek, Mete; Orozco, Luz; Wu, Judy; Qi, Hannah; Pan, Calvin; Packard, René Sevag R; Eskin, Eleazar; Yan, Mujing; Kirchgessner, Todd; Wang, Zeneng; Li, Xinmin; Gregory, Jill C; Hazen, Stanley L; Gargalovic, Peter S; JLusis, Aldons

Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. Journal Article

PLoS Genet, 11 (12), pp. e1005711, 2015, ISSN: 1553-7404.

Abstract | Links | BibTeX | Tags: atherosclerosis, genome-wide association studies, HMDP

2014

Ohmen, Jeffrey; Kang, Eun Yong ; Li, Xin ; Joo, Jong Wha ; Hormozdiari, Farhad ; Zheng, Qing Yin ; Davis, Richard C; Lusis, Aldons J; Eskin, Eleazar ; Friedman, Rick A

Genome-Wide Association Study for Age-Related Hearing Loss (AHL) in the Mouse: A Meta-Analysis. Journal Article

J Assoc Res Otolaryngol, 15 (3), pp. 335-52, 2014, ISSN: 1438-7573.

Abstract | Links | BibTeX | Tags: HMDP, Meta-Analysis, Mouse Genetics

2013

Parks, Brian W; Nam, Elizabeth ; Org, Elin ; Kostem, Emrah ; Norheim, Frode ; Hui, Simon T; Pan, Calvin ; Civelek, Mete ; Rau, Christoph D; Bennett, Brian J; Mehrabian, Margarete ; Ursell, Luke K; He, Aiqing ; Castellani, Lawrence W; Zinker, Bradley ; Kirby, Mark ; Drake, Thomas A; Drevon, Christian A; Knight, Rob ; Gargalovic, Peter ; Kirchgessner, Todd ; Eskin, Eleazar ; Lusis, Aldons J

Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Journal Article

Cell Metab, 17 (1), pp. 141-52, 2013, ISSN: 1932-7420.

Abstract | Links | BibTeX | Tags: HMDP, Mouse Genetics

Davis, Richard C; van Nas, Atila ; Bennett, Brian ; Orozco, Luz ; Pan, Calvin ; Rau, Christoph D; Eskin, Eleazar ; Lusis, Aldons J

Genome-wide association mapping of blood cell traits in mice. Journal Article

Mamm Genome, 2013, ISSN: 1432-1777.

Abstract | Links | BibTeX | Tags: HMDP, Mouse Genetics

2012

Bennett, Brian J; Orozco, Luz ; Kostem, Emrah ; Erbilgin, Ayca ; Dallinga, Marchien ; Neuhaus, Isaac ; Guan, Bo ; Wang, Xuping ; Eskin, Eleazar ; Lusis, Aldons J

High-Resolution Association Mapping of Atherosclerosis Loci in Mice. Journal Article

Arterioscler Thromb Vasc Biol, 2012, ISSN: 1524-4636.

Abstract | Links | BibTeX | Tags: HMDP, Mouse Genetics

Ghazalpour, Anatole; Rau, Christoph D; Farber, Charles R; Bennett, Brian J; Orozco, Luz D; van Nas, Atila; Pan, Calvin; Allayee, Hooman; Beaven, Simon W; Civelek, Mete; Davis, Richard C; Drake, Thomas A; Friedman, Rick A; Furlotte, Nick; Hui, Simon T; Jentsch, David J; Kostem, Emrah; Kang, Hyun Min; Kang, Eun Yong; Joo, Jong Wha; Korshunov, Vyacheslav A; Laughlin, Rick E; Martin, Lisa J; Ohmen, Jeffrey D; Parks, Brian W; Pellegrini, Matteo; Reue, Karen; Smith, Desmond J; Tetradis, Sotirios; Wang, Jessica; Wang, Yibin; N, James

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Journal Article

Mamm Genome, 2012, ISSN: 1432-1777.

Abstract | Links | BibTeX | Tags: HMDP, Mouse Genetics

Calabrese, Gina; Bennett, Brian J; Orozco, Luz ; Kang, Hyun M; Eskin, Eleazar ; Dombret, Carlos ; Backer, Olivier De ; Lusis, Aldons J; Farber, Charles R

Systems genetic analysis of osteoblast-lineage cells. Journal Article

PLoS Genet, 8 (12), pp. e1003150, 2012, ISSN: 1553-7404.

Abstract | Links | BibTeX | Tags: HMDP, Mouse Genetics

2011

Ghazalpour, Anatole; Bennett, Brian; Petyuk, Vladislav A; Orozco, Luz; Hagopian, Raffi; Mungrue, Imran N; Farber, Charles R; Sinsheimer, Janet; Kang, Hyun M; Furlotte, Nicholas; Park, Christopher C; Wen, Ping-Zi; Brewer, Heather; Weitz, Karl; Camp, David G; Pan, Calvin; Yordanova, Roumyana; Neuhaus, Isaac; Tilford, Charles; Siemers, Nathan; Gargalovic, Peter; Eskin, Eleazar; Kirchgessner, Todd; Smith, Desmond J; Smith, Richard D; Lusis, Aldons J

Comparative analysis of proteome and transcriptome variation in mouse. Journal Article

PLoS Genet, 7 (6), pp. e1001393, 2011, ISSN: 1553-7404.

Abstract | Links | BibTeX | Tags: HMDP, Mouse Genetics

Park, Christopher C; Gale, Greg D; de Jong, Simone ; Ghazalpour, Anatole ; Bennett, Brian J; Farber, Charles R; Langfelder, Peter ; Lin, Andy ; Khan, Arshad H; Eskin, Eleazar ; Horvath, Steve ; Lusis, Aldons J; Ophoff, Roel A; Smith, Desmond J

Gene networks associated with conditional fear in mice identified using a systems genetics approach. Journal Article

BMC Syst Biol, 5 , pp. 43, 2011, ISSN: 1752-0509.

Abstract | Links | BibTeX | Tags: HMDP, Mouse Genetics

Farber, Charles R; Bennett, Brian J; Orozco, Luz; Zou, Wei; Lira, Ana; Kostem, Emrah; Kang, Hyun Min; Furlotte, Nicholas; Berberyan, Ani; Ghazalpour, Anatole; Suwanwela, Jaijam; Drake, Thomas A; Eskin, Eleazar; Wang, Tian Q; Teitelbaum, Steven L; Lusis, Aldons J

Mouse genome-wide association and systems genetics identify asxl2 as a regulator of bone mineral density and osteoclastogenesis. Journal Article

PLoS Genet, 7 (4), pp. e1002038, 2011, ISSN: 1553-7404.

Abstract | Links | BibTeX | Tags: HMDP, Mouse Genetics

2010

Bennett, Brian J; Farber, Charles R; Orozco, Luz; Kang, Hyun Min; Ghazalpour, Anatole; Siemers, Nathan; Neubauer, Michael; Neuhaus, Isaac; Yordanova, Roumyana; Guan, Bo; Truong, Amy; Yang, Wen-Pin; He, Aiqing; Kayne, Paul; Gargalovic, Peter; Kirchgessner, Todd; Pan, Calvin; Castellani, Lawrence W; Kostem, Emrah; Furlotte, Nicholas; Drake, Thomas A; Eskin, Eleazar; Lusis, Aldons J

A high-resolution association mapping panel for the dissection of complex traits in mice. Journal Article

Genome Res, 20 (2), pp. 281-90, 2010, ISSN: 1549-5469.

Abstract | Links | BibTeX | Tags: HMDP, Mouse Genetics